| One Thousand Ninety Five (Cognac Barrel Aged) | Kane Brewing Company | | |
| One Thousand Ninety-Five | Kane Brewing Company | | 11.8% |
| One-eyed Ian | B. Nektar Meadery | | 16.0% |
| ONE-OFF [BANISHED] Single-Fruit FreakCake #1 | Crux Fermentation Project | Flanders Oud Bruin | 10.5% |
| One-Two Punch | Granville Island Brewing Company | Belgian IPA | 7.8% |
| Oneida | Modern Times | American Pale Ale | 5.8% |
| Only Brewed 4 Cuban Linx | Strangeways Brewing | Wild Ale | 5.0% |
| The Only Oat Malt Stout In The World | Maclay and Co. | American Stout | |
| Only Schip Worth a Damn | Snipes Mountain / Telegraph / Perennial / Urban Family | | |
| The Only Schip Worth a Damn | Urban Family Brewing | Wild Ale | 6.3% |
| Only Void (coffee) | Tired Hands | American Barleywine | 11.0% |
| Only Void (Red Wine) | Tired Hands | American Imperial Stout | 12.0% |
| Only Void (Rye Whiskey) | Tired Hands | American Imperial Stout | 12.0% |
| Only Void (Stainless) | Tired Hands | American Imperial Stout | 12.0% |
| Onoskelis Barleywine | Palo Alto Brewing Company | English Barleywine | 11.0% |