| Slaapmutske Triple Nightcap | De Proefbrouwerij | | 8.1% |
| Slab Cabin IPA | Otto's Pub and Brewery | American IPA | 5.0% |
| Slacker | No-Li Brewhouse | Herb and Spice Beer | 6.1% |
| Slacktivist | Three Floyds Brewing / Sun King Brewing | Kölsch | 7.3% |
| Sláinte Scottish Style Ale | Central Waters Brewing Company | Scotch Ale / Wee Heavy | 7.5% |
| Slam Dunkel | Manayunk Brewery and Restaurant | | |
| Slam Dunkelweizen | Big Time Brewing | | 8.0% |
| Slap Fight | Monday NIght Brewing | American IPA | 5.8% |
| Slap Yer Mammy | Trinity Brewing Company | Imperial IPA | 10.5% |
| Sled Dog Doppelbock | Wagner Valley Brewing | Bock | |
| Sled Dog Trippel Bock | Wagner Valley Brewing | Doppelbock | 10.0% |
| Sleep Over Coffee IIPA | To Øl | Imperial IPA | 10.5% |
| Sleeper Car Whiskey Cask Edition | Cassel Brewery Co. | American Porter | 8.2% |
| Sleeper Street | Trillium Brewing Company | American IPA | 7.1% |
| Sleepin' With Shaggy | Green Flash Brewing Co. | American Barleywine | 12.5% |