| Two Guns Pilsner | Wynkoop Brewing | German Pilsner | 5.0% |
| Two Hearted Ale | Bell's Brewery, Inc. | American IPA | 7.0% |
| Two Hearts of Fire | WTP Brewing | | 9.2% |
| Two Jokers Double-Wit | Boulevard Brewing Company | Witbier | 8.0% |
| Two Lions Pale Ale | Taylor's Crossing Brewing | American Pale Ale | |
| Two Penny Porter | Birrificio Ticinese | American Porter | 8.2% |
| Two Pilots | Sante Adairius Rustic Ales | Saison | 7.0% |
| Two Regular Joe's: Kettle Sour Pale Ale | Nantahala Brewing | | |
| Two Regular Joes | Cigar City Brewing | American Imperial Stout | 9.3% |
| Two Sisters Imperial Stout | Amherst Brewing Company | American Imperial Stout | 6.7% |
| Two Term Double IPA | Diamond Bear Brewing Co. | Imperial IPA | |
| Two Tortugas | Karl Strauss Brewing Company | Quadrupel (Quad) | 11.1% |
| Two Tugs | Half Acre Beer Company | American Brown Ale | 8.0% |
| Two Women | New Glarus Brewing Company | German Pilsner | 5.0% |
| Two-Hearted Ale | Kalamazoo Brewing | American Pale Ale | |