| Universal Friend Juicy Grape Saison | Modern Times | Saison | 7.2% |
| UniversAle Pale | Fremont Brewing Company | American Pale Ale | 5.6% |
| Unknown | Shmaltz Brewing Company | | |
| Unknown Soldier | The Livery | Wild Ale | |
| Unleash The Yeast: American Ale | BrewDog Ltd | American Pale Ale | 6.3% |
| Unleash The Yeast: Bavarian Weizen | BrewDog Ltd | Hefeweizen | 6.3% |
| Unleash The Yeast: Belgian Trappist | BrewDog Ltd | Belgian Pale Ale | 6.3% |
| Unleash The Yeast: Pilsen Lager | BrewDog Ltd | American Lager | 6.3% |
| Unnamed | Forest & Main | | 6.0% |
| Uno Mas | Hoppers Seafood & Grill | American Lager | |
| Unobtainium | Straight to Ale Brewing | | |
| Unobtainium Barrel-Aged Old Ale | Straight to Ale Brewing | Old Ale | 11.5% |
| Unorthodox | Two Roads Brewing Co. | Russian Imperial Stout | 9.2% |
| Unplugged Abt | New Glarus Brewing Company | | |
| Unplugged Bourbon Barrel Bock | New Glarus Brewing Company | Doppelbock | |