| Secessionist #1 (Gingerbread Stout) | Buffalo Bayou | American Imperial Stout | 10.0% |
| Second Anniversary - Grand Cru | Figueroa Mountain Brewing Co. | Belgian Dark Strong Ale | 10.7% |
| Second Anniversary Ale | Hardywood Park Craft Brewery | Tripel | 10.5% |
| Second Breakfast | Night Shift Brewing | Baltic Porter | 10.8% |
| The Second Coming | Right Brain Brewery | Imperial IPA | 8.0% |
| Second Fiddle | Fiddlehead Brewing | Imperial IPA | 8.2% |
| Second Hand Smoke | Midnight Sun Brewing Co. | American Stout | 8.4% |
| Second nature | Kent Falls Brewing Company | Wild Ale | 5.6% |
| Second Street IPA | Second Street Brewery | American IPA | 6.0% |
| Second Wind Pale Ale | Mother Earth Brewing | American Pale Ale | 5.0% |
| Secret Admirer | Alewerks Brewing Company | Imperial IPA | 8.3% |
| Secret Admirer | Williamsburg AleWerks | Imperial IPA | 8.0% |
| Secret Angel | Wicked Weed | | |
| Secret Santa | Amager Bryghus | Quadrupel (Quad) | 10.5% |
| Secret Spot - 2013 Anniversary Ale | Green Room Brewing | American Imperial Stout | 10.0% |