| Secret Spot 2016 | Green Room Brewing | American Imperial Stout | 11.0% |
| Secret Spot- 2015 | Green Room Brewing | Russian Imperial Stout | 10.0% |
| Secret Stache Stout | Finch's Beer Co. | | 5.3% |
| Secret Stairs | Trillium | American Stout | 6.5% |
| Secret Stairs | Trillium Brewing Company | American Stout | 6.5% |
| Sede Vacante | The Lost Abbey | American Strong Ale | 15.0% |
| Sedici Gradi | Birra Del Borgo | | |
| Seduction | Brewery Ommegang | Belgian Dark Ale | 6.8% |
| See the Stars | Creature Comforts | American Imperial Stout | 10.9% |
| See-Weizen Bio-Hefeweizen | Brauerei & Gasthof zur Krone | Hefeweizen | |
| Seef | Antwerpse Brouw Compagnie | Belgian Pale Ale | 6.5% |
| Seeing Double IPA | Foothills Brewing Company | Imperial IPA | 9.5% |
| Seek & Destroy | Black Market Brewing Company | Smoked Beer | 12.1% |
| Seeking Alpha | Captain Lawrence Brewing Company | | |
| The Seer | Holy Mountain | Saison | 6.5% |