| Slumbrew | Massachusetts |
| Sly Fox Brewhouse and Eatery - Phoenixville | Phoenixville, Pennsylvania |
| Sly Fox Brewhouse and Eatery - Royersford | Royersford, Pennsylvania |
| Sly Fox Brewing Company | Pottstown , Pennsylvania |
| Small Town Brewery | Wauconda |
| Smartmouth | Norfolk, Virginia |
| Smazinheira Brewing | |
| Smithwick's Brewery | Ireland |
| Smog City Brewing Company | Torrance, California |
| Smoky Mountain Brewing | Knoxville, Tennessee |
| Smuttlabs | Portsmouth, New Hampshire |
| Smuttynose Brewing Co. | Portsmouth, New Hampshire |
| SNAB | |
| Snake River Brewing | Jackson, Wyoming |
| Sneaky Snake Brewery | Athens |